# Stable Cell Line Generation - Creative Biogene > A leading provider for stable cell lines, virus particles, gene-editing services, RNA synthesis & functional studies, and microbiology services for the life science community. Creative Biogene provides comprehensive products and services for life science research, spanning stable cell lines, viral particles, host cell protein and residual DNA assays, gene editing, drug discovery screening, and cell & gene therapy solutions. ## Products - [Host Cell Protein Assay Kits](https://www.creative-biogene.com/products/host-cell-protein-assay-kits.html): Creative Biogene is a leading biotechnology company which has the expertise in providing host cell protein assay services and related products for customers worldwide. - [Residual DNA Quantification Kits](https://www.creative-biogene.com/products/residual-dna-quantification-kit.html): Creative Biogene offers a variety of q-PCR based residual DNA quantification kits for your research. - [Premade AAV Particles](https://www.creative-biogene.com/products/premade-aav-particles.html): We have a large selection of AAV products, spanning human, mouse, and rat genes, as well as many AAV controls, fluorescent reporters, Cre/FLP recombinases, calcium sensors, and optogenetic reporters. - [Premade Adenovirus Particles](https://www.creative-biogene.com/products/premade-adenovirus-particles.html): Creative Biogene has developed a comprehensive library of human, mouse and rat genes cloned into adenoviral vectors or ready-to-use lentivirus, which can be used to manipulate the expression of your gene of interest within a wide range of host cells. - [Premade Lentivirus Particles](https://www.creative-biogene.com/products/premade-lentivirus-particles.html): Our comprehensive suite of lentiviral solutions includes ready-to-use particles suitable for use in cell culture and animals, plasmid clones expressing ORF, miRNA, shRNA, and sgRNA. - [Gene Knockout Stable Cell Lines](https://www.creative-biogene.com/products/gene-knockout-stable-cell-lines.html): 2500+ KO cell products in stock (covering 500+ genes and 35+ cell types), fast feedback (within 24 h) and short turnaround time (within 1 week), monoclonal KO cells validated by Sanger sequencing. - [Cas9 Stable Cell Lines](https://www.creative-biogene.com/products/cas9-stable-cell-lines.html): Creative Biogene has developed a series of Cas9 expressing stable cell lines. - [Immune Receptor Stable Cell Lines](https://www.creative-biogene.com/products/immune-receptor-stable-cell-lines.html): To accelerate the research progress of immune-checkpoint proteins, we have developed stable cell lines expressing the most popular immune checkpoints. - [Reporter Stable Cell Lines](https://www.creative-biogene.com/products/reporter-stable-cell-lines.html): Enhance research with Creative Biogene's diverse, reliable Reporter Cell Lines. Tailored options, mycoplasma-free assurance, and customization services are available. - [Kinase Stable Cell Lines](https://www.creative-biogene.com/products/kinase-stable-cell-lines.html): Creative Biogene has developed a large collection of kinase stable cell lines that can be used for in vitro cell-based kinase assays. - [Recombinase AAV Particles](https://www.creative-biogene.com/products/recombinase-aav-particles.html): Creative Biogene has a wide variety of Cre recombinase AAV particles. - [Cell Immortalization Lentiviral Particles](https://www.creative-biogene.com/products/cell-immortalization-lentiviral-particles.html): Creative Biogene offers lentiviral particles that can be used for developing immortalized cell line. - [Biosimilar Stable Cell Lines](https://www.creative-biogene.com/products/biosimilar-stable-cell-lines.html): Creative Biogene has years of experience in stable cell line development. Our scientists have successfully expressed biologics including full antibodies, antibody fragments, bispecific antibodies, fusion proteins and growth factors. - [dsRNA Control](https://www.creative-biogene.com/products/dsrna-control.html): Creative Biogene can provide several versions of dsRNA controls which could be used as a positive control to help your dsRNA assays. - [Recombinant Drug Target Proteins](https://www.creative-biogene.com/recombinant-drug-target-proteins.html): Discover premium recombinant drug target proteins for biomedical research. 500+ hot drug target proteins with validated bioactivity, from kinases to receptors. ISO 9001:2015 certified quality. - [AAV Titer Detection Kits](https://www.creative-biogene.com/aav-titer-detection-kits.html): Creative Biogene has developed a comprehensive range of AAV titer detection kits designed to provide researchers with accurate and reliable AAV vector quantification. - [Custom RNA Service](https://www.creative-biogene.com/custom-rna-service.html): Custom RNA design, synthesis, and GMP production services by Creative Biogene—covering mRNA, saRNA, circRNA, and RNAi for research and drug development. ## Services - [Biosafety Testing Service](https://www.creative-biogene.com/Services/Biosafety-Testing-Service.html): Biosafety testing services for viral vectors and cell & gene therapy products. - [AAV Service](https://www.creative-biogene.com/Services/Custom-Viral-Service/AAV-service.html): Explore Creative Biogene's advanced AAV vector solutions, providing precise tissue targeting, optimized gene delivery, and scalable production for gene therapy research and clinical applications. Learn about our innovative services, including AAV vector design, production, purification, capsid engineering, and biodistribution detection, all backed by a comprehensive quality control system to meet global regulatory standards. - [Adenovirus Service](https://www.creative-biogene.com/Services/Custom-Viral-Service/Adenovirus-service.html): High-quality adenovirus vector services including Ad5, Ad5/35 & HDAd construction, amplification & purification with advanced QVirus™ platform. - [Lentivirus Service](https://www.creative-biogene.com/Services/Custom-Viral-Service/Lentivirus-service.html): Creative Biogene's lentivirus service ensures high titers, regulatory compliance, and scalable production: custom CAR lentivirus solutions, CRISPR delivery, and IND-supporting QC. - [Retrovirus Service](https://www.creative-biogene.com/Services/Custom-Viral-Service/Retrovirus-service.html): Explore Creative Biogene's retrovirus vector services offering CRO and GMP-grade CDMO solutions for gene therapy, T cell engineering, and stem cell modification. Robust QC, flexible pseudotyping, and IND-ready documentation. - [GPCR Stable Cell Line Development](https://www.creative-biogene.com/Services/GPCR-cell-line-development.html): With years of experience and thousands of accomplished projects, Creative Biogene offers flexible GPCR detection solutions which can help customer to achieve an ideal GPCR stable cell line suitable for downstream cell-based assay. - [Stable Knockout Cell Line Generation](https://www.creative-biogene.com/Services/Stable-cell-line-generation/Custom-Genome-Editing-Cell-Lines.html): Generate high-quality, stable knockout cell lines with CRISPR/Cas9. Creative Biogene offers single, multiplex, and fragment deletion knockout (KO) models for research and drug discovery. - [Target-based Drug Discovery Service](https://www.creative-biogene.com/Services/Drug-Discovery-Services/Target-based-Screening.html): Accelerate your R&D with end-to-end target-based drug discovery services, integrating target validation, high-throughput screening, SAR-driven lead optimization, and early ADME-Tox insight to deliver clinically relevant, mechanism-informed drug candidates. - [Ion Channel Screening & Profiling Services](https://www.creative-biogene.com/Services/Drug-Discovery-Services/Ion-Channel-Screening-Assays.html): Creative Biogene has generated an extensive panel of ion channel screening assays comprising more than 80 ion channel targets and over 200 ion channel assays. In terms of conventional patch clamp electrophysiology, automated electrophysiology, and fluorescence assays, Creative Biogene can offer a wide range of binding and functional assays for ion channel assays to quickly and accurately provide results for drug discovery. - [Kinase Screening & Profiling Services](https://www.creative-biogene.com/Services/Drug-Discovery-Services/Kinase-Screening-Assays.html): Creative Biogene can provide you gold-standard filter-binding radiometric kinase activity assays, TR-FRET technology, and mobility shift assays to measure substrate phosphorylation, and also the kinase assays to detect ATP consumption and ADP generation. - [Plant Genetic Modification Service](https://www.creative-biogene.com/services/transgenic-plant-service.html): Creative Biogene offers comprehensive Plant Genetic Modification Services integrating gene editing, vector construction, transformation, molecular testing, and functional validation. Our platform supports a wide range of plant species—from model and cereal crops to horticultural and oil plants—using advanced CRISPR, base, and prime editing technologies. - [Virus-Like Particles (VLPs) Service](https://www.creative-biogene.com/services/virus-like-particles-vlps-service.html): Creative Biogene is committed to providing you the best VLP-based services. Tell us how we could help you today. - [AAV Capsid Evolution & Screening Service](https://www.creative-biogene.com/services/aav-capsid-evolution-screening-service.html): Creative Biogene has established a comprehensive platform for discovering novel AAV candidates, from construction of AAV capsid plasmid libraries, to produce the viral libraries containing diverse AAV capsid variants, to perform in vitro selection by target cell infection and/or in vivo selection using mouse or non-human primates (NHP) as models. - [Gene Editing Services](https://www.creative-biogene.com/services/gene-editing-services.html): Creative Biogene provides advanced Gene Editing technology and related services to help clients make progress in basic biology research, disease research, and drug discovery. - [mcDNA Production Service](https://www.creative-biogene.com/services/mcdna-production-service.html): Comprehensive mcDNA synthesis and customization services for gene therapy applications, offering high-quality minicircle DNA production with enhanced safety, sustained expression, and GMP-compliant manufacturing capabilities. - [Single Domain Antibody Development and Production](https://www.creative-biogene.com/services/single-domain-antibody-development-and-production.html): Creative Biogene's offerings span from antigen-specific library construction to high-throughput screening, expression, and validation. We provide natural, immunized, and synthetic single domain antibody libraries tailored to your project's needs. - [Monoclonal Antibody Development and Production Service](https://www.creative-biogene.com/services/monoclonal-antibody-development-and-production-service.html): Creative Biogene offers comprehensive monoclonal antibody development and production services, from antigen design to GMP manufacturing. With advanced technology platforms, scalable production, and stringent quality control, we help clients overcome industry challenges and accelerate commercialization. ## CDMO Services - [CAR-T Cell Development Services](https://www.creative-biogene.com/cdmo/car-t-cell-development-services.html): Creative Biogene provides customized development services to help our clients address CAR-T cell production workflow challenges, thereby accelerating the progress of their projects. - [Scalable Lentiviral Vector Production Service](https://www.creative-biogene.com/cdmo/scalable-lentiviral-vector-production-service.html): Creative Biogene uses HEK293SF cell lines for scale-up production of lentiviral vectors to help customers address challenges in LV production and achieve robust and scalable LV commercialization and mass production. ## AI-Driven Solutions - [AI-Driven Gene Editing and Therapy](https://www.creative-biogene.com/ai/ai-driven-gene-editing-and-therapy.html): Creative Biogene's AI-Driven Gene Editing and Therapy service integrates advanced artificial intelligence technology with deep learning algorithms to offer personalized solutions for gene editing. ## Applications - [Cell & Gene Therapy Biosafety Testing](https://www.creative-biogene.com/applications/cell-gene-therapy-biosafety-testing.html): Biosafety testing applications for cell and gene therapy research. - [Membrane Proteome Chip Antibody Off-Target Screening Service](https://www.creative-biogene.com/applications/membrane-proteome-chip-antibody-off-target-screening-service.html): Off-target screening service for antibodies using membrane proteome chips.